Prof. Dr. Wolfgang Gaebel

Research Interest

Our research in the field of psychiatry and psychotherapy is guided by the conception of mental disorders as biopsychosocial disorders. As part of this interest, the group is actively involved in the Düsseldorf DFG Collaborative Research Centre 991 “The Structure of Representations in Language, Cognition, and Science” with a research project on the application of frame theory to the conception of mental disorders. Another research focus is the classification of mental disorders, especially psychotic disorders, and there is an active participation  in both the development processes of DSM-5 (American Psychiatric Association) and ICD-11 (World Health Organisation). As regards the biological foundations of mental disorders, investigations deal with  the roles of genetics, protein biochemistry, and disturbed neurocircuits (using EEG and MRT) in the pathophysiology of mental disorders. In the psychological field, the focus is on developing psychotherapeutic interventions especially in schizophrenia. In the field of social causes of mental disorders, the main research interest is the stigmatization of people with mental disorders and ways how to reduce this stigmatization (research project for the World Psychiatric Association). Furthermore, our research groups participate in multicenter clinical trials to improve the pharmacological treatment of mental disorders including the improved recognition and treatment of early stages of severe mental disorders like schizophrenia. Another major aspect is healthcare research in the field of mental disorders, with research projects being coordinated for the Federal Medical Chamber (Mental healthcare utilization in Germany) and the German Society for Psychiatry (development of quality indicators for mental healthcare, development of the updated S3 Guideline “Schizophrenia”).

Selected Publications

1. Remediation of impairments in facial affect recognition in schizophrenia: efficacy and specificity of a new training program. Wölwer W, Frommann N, Halfmann S, Piaszek A, Streit M, Gaebel W. Schizophr Res. 2005 Dec 15;80(2-3):295-303. undefinedPubMed

2. Evaluation of the German WPA "program against stigma and discrimination because of schizophrenia--Open the Doors": results from representative telephone surveys before and after three years of antistigma interventions. Gaebel W, Zäske H, Baumann AE, Klosterkötter J, Maier W, Decker P, Möller HJ. Schizophr Res. 2008 Jan;98(1-3):184-93. undefinedPubMed

3. Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial. Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IP, Gheorghe MD, Rybakowski JK, Galderisi S, Libiger J, Hummer M, Dollfus S, López-Ibor JJ, Hranov LG, Gaebel W, Peuskens J, Lindefors N, Riecher-Rössler A, Grobbee DE; EUFEST study group. Lancet. 2008 Mar 29;371(9618):1085-97. undefinedPubMed

4. Global pattern of experienced and anticipated discrimination against people with schizophrenia: a cross-sectional survey. Thornicroft G, Brohan E, Rose D, Sartorius N, Leese M; INDIGO Study Group. Lancet. 2009 Jan 31;373(9661):408-15. undefinedPubMed

5. Mental health quality, outcome measurement, and improvement in Germany. Gaebel W, Janssen B, Zielasek J. Curr Opin Psychiatry. 2009 Nov;22(6):636-42. undefinedPubMed

6. Future classification of psychotic disorders. Gaebel W, Zielasek J. Eur Arch Psychiatry Clin Neurosci. 2009 Nov;259 Suppl 2:S213-8. undefinedPubMed

7. Relapse prevention in first-episode schizophrenia--maintenance vs intermittent drug treatment with prodrome-based early intervention: results of a randomized controlled trial within the German Research Network on Schizophrenia. Gaebel W, Riesbeck M, Wölwer W, Klimke A, Eickhoff M, von Wilmsdorff M, Lemke M, Heuser I, Maier W, Huff W, Schmitt A, Sauer H, Riedel M, Klingberg S, Köpcke W, Ohmann C, Möller HJ; German Study Group on First-Episode Schizophrenia. J Clin Psychiatry. 2011 Feb;72(2):205-18. undefinedPubMed

8. Modular networks involving the medial frontal cortex: towards the development of neuropsychiatry. Seitz RJ, Gaebel W, Zielasek J. World J Biol Psychiatry. 2011 Jun;12(4):249-59. undefinedPubMed

9. Integrative etiopathogenetic models of psychotic disorders: methods, evidence and concepts. Gaebel W, Zielasek J. Schizophr Bull. 2011 Sep;37 Suppl 2:S5-12. undefinedPubMed

10. Schizophrenia guidelines across the world: A selective review and comparison. Gaebel W, Riesbeck M, Wobrock T. Int Rev Psychiatry. 2011 Aug;23(4):379-87. undefinedPubMed

Prof. Dr.
Wolfgang Gaebel


Prof. Dr. Wolfgang Gaebel

Dept. of Psychiatry and Psychotherapy
LVR Klinikum Düsseldorf
Kliniken der Heinrich-Heine Universität
Bergische Landstr. 2

Fax: 0211-922-2020
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