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Neuroscience Network Düsseldorf

The Neuroscience Network Düsseldorf is a collaborative research network in which basic and clinical neuroscientists from the Heinrich Heine University (HHU) Düsseldorf, the Research Centre Jülich, and the IUF - Leibniz Research Institute for Environmental Medicine Düsseldorf work together in multidisciplinary projects ranging from basic brain research to translational and clinical neuroscience.

A particular focus is placed on the investigation of disease-associated pathomechanisms in common diseases of the central nervous system, in particular multiple sclerosis, Alzheimer's and Parkinson's diseases, brain tumours, traumatic brain and spinal cord injury, and metabolic encephalopathies. These diseases constitute a major medical problem in our society and pose enormous socio-economic challenges. Thus, the common research aim of the participating groups is to improve the understanding of molecular, cellular and systemic mechanisms causing these diseases, and to translate novel experimental findings into better diagnostic tools and more effective therapies.

In addition, excellent research training opportunities for junior researchers from both medicine and the natural sciences are offered, including structured programmes that provide master students, as well as doctoral and postdoctoral researchers with the instruction, research experience and mentoring they need to become future leaders in disease-related neuroscience research.



Recent Publications

| NND-Publikationen

Olejarz-Maciej et al., Molecules. 2023

Trisubstituted 1,3,5-Triazines as Histamine H4 Receptor Antagonists with Promising Activity In Vivo.

| NND-Publikationen

Staszewski et al., Pharmaceuticals (Basel). 2023

Guanidines: Synthesis of Novel Histamine H3R Antagonists with Additional Breast Anticancer Activity and Cholinesterases…

| NND-Publikationen

Valinciute et al., J Neurooncol. 2023

Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.

| NND-Publikationen

Heckner et al., Cereb Cortex. 2023

Predicting executive functioning from functional brain connectivity: network specificity and age effects.

| NND-Publikationen

Nelke et al., JCI Insight. [in press]

Eculizumab treatment alters the proteometabolome beyond the inhibiton of complement.

| NND-Publikationen

Aktas et al., J Neurol Neurosurg Psychiatry. [in press]

Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by…

| NND-Publikationen

Marković et al., Chem Biol Interact. [in press]

Thiazole derivatives as dual inhibitors of deoxyribonuclease I and 5-lipoxygenase: A promising scaffold for the…

| NND-Publikationen

Krösche et al., Mov Disord. [in press]

Slowing of Frontal β Oscillations in Atypical Parkinsonism.

| NND-Publikationen

Hartmann et al., Cells. 2023

Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on…

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