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Director of the Department of Psychiatry and Psychotherapy

Prof. Dr. Eva Meisenzahl
Department of Psychiatry and Psychotherapy
Heinrich-Heine-University
c/o LVR-Klinikum Düsseldorf
Bergische Landstr. 2
40629 Düsseldorf

Research Interest
  • Early recognition and prevention of psychiatric disorders in close cooperation between adolescent psychiatry
  • Development of prognostic AI tools by use of pattern recognition (data science and ML-expertise)
  • Investigation of neurobiological causes of functional psychoses and personality disorders,
  • In Biomarkers, focus on Multimodal Imaging and Imaging Genomics
  • Development of E-mental health Digital and Education Programmes
Further information
Selected Publications
  1. Nikolaos Koutsouleris, Dominic B Dwyer, Franziska Degenhardt, Carlo Maj, Maria Fernanda Urquijo-Castro, Rachele Sanfelici, David Popovic, Oemer Oeztuerk, Shalaila S Haas, Johanna Weiske, Anne Ruef, Lana Kambeitz-Ilankovic, Linda A Antonucci, Susanne Neufang, Christian Schmidt-Kraepelin, Stephan Ruhrmann, Nora Penzel, Joseph Kambeitz, Theresa K Haidl, Marlene Rosen, Katharine Chisholm, Anita Riecher-Rössler, Laura Egloff, André Schmidt, Christina Andreou, Jarmo Hietala, Timo Schirmer, Georg Romer, Petra Walger, Maurizia Franscini, Nina Traber-Walker, Benno G Schimmelmann, Rahel Flückiger, Chantal Michel, Wulf Rössler, Oleg Borisov, Peter M Krawitz, Karsten Heekeren, Roman Buechler, Christos Pantelis, Peter Falkai, Raimo K R Salokangas, Rebekka Lencer, Alessandro Bertolino, Stefan Borgwardt, Markus Noethen, Paolo Brambilla, Stephen J Wood, Rachel Upthegrove, Frauke Schultze-Lutter, Anastasia Theodoridou, Eva Meisenzahl, Writing Group for the PRONIA Consortium. Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression. JAMA Psychiatry. 2020 Dec 2;e203604. doi: 10.1001/jamapsychiatry.2020.3604. Online ahead of print. PubMed
  2. Nikolaos Koutsouleris, Lana Kambeitz-Ilankovic, Stephan Ruhrmann, Marlene Rosen, Anne Ruef, Dominic B Dwyer, Marco Paolini, Katharine Chisholm, Joseph Kambeitz, Theresa Haidl, André Schmidt, John Gillam, Frauke Schultze-Lutter, Peter Falkai, Maximilian Reiser, Anita Riecher-Rössler, Rachel Upthegrove, Jarmo Hietala, Raimo K R Salokangas, Christos Pantelis, Eva Meisenzahl, Stephen J Wood, Dirk Beque, Paolo Brambilla, Stefan Borgwardt, PRONIA Consortium. Prediction Models of Functional Outcomes for Individuals in the Clinical High-Risk State for Psychosis or With Recent-Onset Depression: A Multimodal, Multisite Machine Learning Analysis. JAMA Psychiatry. 2018 Nov 1;75(11):1156-1172. doi: 10.1001/jamapsychiatry.2018.2165. PubMed
  3. Nikolaos Koutsouleris, Eva M Meisenzahl, Stefan Borgwardt, Anita Riecher-Rössler, Thomas Frodl, Joseph Kambeitz, Yanis Köhler, Peter Falkai, Hans-Jürgen Möller, Maximilian Reiser, Christos Davatzikos. Individualized differential diagnosis of schizophrenia and mood disorders using neuroanatomical biomarkers. Brain. 2015 Jul;138(Pt 7):2059-73. doi: 10.1093/brain/awv111. Epub 2015 May 1. PubMed
  4. Nikolaos Koutsouleris, Christos Davatzikos, Stefan Borgwardt, Christian Gaser, Ronald Bottlender, Thomas Frodl, Peter Falkai, Anita Riecher-Rössler, Hans-Jürgen Möller, Maximilian Reiser, Christos Pantelis, Eva Meisenzahl. Accelerated brain aging in schizophrenia and beyond: a neuroanatomical marker of psychiatric disorders. Schizophr Bull. 2014 Sep;40(5):1140-53. doi: 10.1093/schbul/sbt142. Epub 2013 Oct 13. PubMed
  5. Stefan Borgwardt, Nikolaos Koutsouleris, Jacqueline Aston, Erich Studerus, Renata Smieskova, Anita Riecher-Rössler, Eva M Meisenzahl. Distinguishing prodromal from first-episode psychosis using neuroanatomical single-subject pattern recognition. Schizophr Bull. 2013  Sep;39(5):1105-14. doi: 10.1093/schbul/sbs095. Epub 2012 Sep 11. PubMed
  6. Nikolaos Koutsouleris, Christos Davatzikos, Ronald Bottlender, Katja Patschurek-Kliche, Johanna Scheuerecker, Petra Decker, Christian Gaser, Hans-Jürgen Möller, Eva M Meisenzahl. Early recognition and disease prediction in the at-risk mental states for psychosis using neurocognitive pattern classification. Schizophr Bull. 2012 Nov;38(6):1200-15. doi: 10.1093/schbul/sbr037. Epub 2011 May 16. PubMed
  7. Nikolaos Koutsouleris, Eva M Meisenzahl, Christos Davatzikos, Ronald Bottlender, Thomas Frodl, Johanna Scheuerecker, Gisela Schmitt, Thomas Zetzsche, Petra Decker, Maximilian Reiser, Hans-Jürgen Möller, Christian Gaser. Use of neuroanatomical pattern classification to identify subjects in at-risk mental states of psychosis and predict disease transition. Arch Gen Psychiatry. 2009 Jul;66(7):700-12. doi: 10.1001/archgenpsychiatry.2009.62. PubMed
  8. T Frodl, N Koutsouleris, R Bottlender, C Born, M Jäger, M Mörgenthaler, J Scheuerecker, P Zill, T Baghai, C Schüle, R Rupprecht, B Bondy, M Reiser, H-J Möller, E M Meisenzahl. Reduced gray matter brain volumes are associated with variants of the serotonin transporter gene in major depression. Mol Psychiatry. 2008 Dec;13(12):1093-101. doi: 10.1038/mp.2008.62. Epub 2008 Jul 1. PubMed
  9. Thomas S Frodl, Nikolaos Koutsouleris, Ronald Bottlender, Christine Born, Markus Jäger, Isabel Scupin, Maximilian Reiser, Hans-Jürgen Möller, Eva M Meisenzahl. Depression-related variation in brain morphology over 3 years: effects of stress? Arch Gen Psychiatry. 2008 Oct;65(10):1156-65. doi: 10.1001/archpsyc.65.10.1156. PubMed
  10. Thomas Frodl, Cornelius Schüle, Gisela Schmitt, Christine Born, Thomas Baghai, Peter Zill, Ronald Bottlender, Rainer Rupprecht, Brigitta Bondy, Maximilian Reiser, Hans-Jürgen Möller, Eva M Meisenzahl. Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression. Arch Gen Psychiatry. 2007 Apr;64(4):410-6. doi: 10.1001/archpsyc.64.4.410. PubMed
  11. D Rujescu, E M Meisenzahl, S Krejcova, I Giegling, T Zetzsche, M Reiser, C M Born, H-J Möller, A Veske, A Gal, U Finckh. Plexin B3 is genetically associated with verbal performance and white matter volume in human brain. Mol Psychiatry. 2007 Feb;12(2):190-4, 115. doi: 10.1038/sj.mp.4001903. Epub 2006 Oct 10. PubMed
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