PD Dr. rer. nat. Jan Hirschmann
Institute of Clinical Neuroscience and Medical PsychologyMedical Faculty
Heinrich Heine University
Universitätsstr. 1
40225 Düsseldorf Nordrhein-Westfalen
Research Interest
I am interested in the human motor system, its involvement and interactions with cognition, and its alterations in movement disorders, such as Parkinson’s disease. With respect to methods, I focus on electrophysiology. In particular, my lab specialises in the combination of invasive recordings from deep brain electrodes and non-invasive recording techniques, such as MEG or EEG. In addition, we specialise in applied machine learning for neurology and deep brain stimulation, in particular.
Further information
Selected Publications
- Rassoulou, F., Sharma, A., Steina, A., Butz, M., Hartmann, C. J., Bahners, B. H., ... & Hirschmann, J. (2025). Electrophysiological signatures predict the therapeutic window of deep brain stimulation electrode contacts. npj Digital Medicine, 8(1), 635. 10.1038/s41746-025-02089-w.
- Winkler, L., Werner, L. M., Butz, M., Hartmann, C. J., Schnitzler, A., & Hirschmann, J. (2025). Deep brain stimulation-responsive subthalamo-cortical coupling in obsessive-compulsive disorder. Brain Stimulation, 19(1), 103008. 10.1016/j.brs.2025.103008.
- Steina, A., Sure, S., Butz, M., Vesper, J., Schnitzler, A., Hirschmann, J. (2025). Oscillatory coupling between thalamus, cerebellum and motor cortex in essential tremor. Movement Disorders, 40(5), 896-905. 10.1002/mds.30165.
- Werner, L.M., Schnitzler, A., Hirschmann, J. (2025) Subthalamic nucleus deep brain stimulation in the beta frequency range boosts cortical beta oscillations and slows down movement. Journal of Neuroscience, 45(9). 10.1523/JNEUROSCI.1366-24.2024.
- Winkler, L., Butz, M., Sharma, A., Vesper, J., Schnitzler, A., Fischer, P., Hirschmann, J. (2025) Beta Waves in Action: Context-Dependent Modulations of Subthalamo-Cortical Synchronization during Rapid Reversals of Movement Direction. eLife, 13. https://doi.org/10.7554/eLife.101769.1.
- Krösche, M., Hartmann, C. J., Butz, M., Schnitzler, A., & Hirschmann, J. (2025). Altered cortical network dynamics during observing and preparing action in patients with corticobasal syndrome. Neurobiology of Disease, 205, 106796. 10.1016/j.nbd.2025.106796.
- Rassoulou, F., Steina, A., Hartmann, C.J., Vesper, J., Butz, M., Schnitzler, A., Hirschmann, J. (2024) Exploring the electrophysiology of Parkinson’s disease with magnetoencephalography and deep brain recordings. Scientific Data, 11:1(2024). 10.1038/s41597-024-03768-1.
- Steina, A., Sure S., Butz, M., Vesper, J., Schnitzler, A. Hirschmann, J. (2024). Mapping subcortico-cortical coupling – a comparison of thalamic and subthalamic oscillations. Movement Disorders, 39.4 (2024):684693. 10.1002/mds.29730.
- Kroesche, M., Kannenberg, S., Butz, M., Hartmann, C., Florin, E., Schnitzler, A., & Hirschmann, J. Slowing of Frontocentral Beta Oscillations in Atypical Parkinsonism. Movement Disorders (2023), 38(5), 10.1002/mds.29378.
- Hirschmann, J, Steina, A., Vesper, J., Florin, E., & Schnitzler, A. (2022). Neuronal oscillations predict deep brain stimulation outcome in Parkinson’s disease. Brain Stimulation (2022), 15(3), 792-802. 10.1016/j.brs.2022.05.008.